Fecal microbiota transplantation (FMT) has become an emerging modality for patients suffering from C diff. Some studies have shown that FMT of stool from a healthy donor in a sick patient is very effective, demonstrating that the procedure can resolve 80-90% of infections caused by recurrent infections. C difference..
The most common procedure for administering FMT is colonoscopy followed by a nasogastric tube and enema. Encapsulation is a more convenient and less invasive way to administer FMT. However, there is no standardized method for stool encapsulation (microbiome). The process is time-consuming and inefficient to the point that its availability to patients may be limited and does not allow comparison of results and data between different studies because each laboratory or supplier has its own preparation procedure.
One company, Tend, developed its Gut Microbiome Collect and Prep (CAP) device to standardize stool encapsulation for FMT. The startup announced the launch of clinical studies for the device in March.
Contagion spoke to Tend CMO and co-founder Tom Lendvay, MD, who provided some background on the device, the new study, the company’s new relationship with Massachusetts General Hospital, and how the device can help FMT in its whole.