“A patient presented with a high-grade stenosed lesion in a brachiocephalic venous outflow-limiting fistula. The lesion was resistant to initial treatment using high-pressure ATP inflated to 40 atmospheres (ATM). The lesion was subsequently treated with the XO Score device and followed by obliteration of the stenosis with a standard PTA balloon inflated to nominal pressure (9 ATM) There was no residual stenosis and the fistula was no longer pulsatile on examination . shared Dr. Jeffrey Hogardinterventional nephrologist at the Raleigh Access Center in Raleigh, North Carolina. “XO Score presented us with an excellent treatment option for high pressure ATP failure.”
Another recent case involved an ATP-resistant lesion in a brachiobasilic graft with flow-limiting outflow stenosis. The lesion did not respond to an inflated PTA at 22 ATM. Initial treatment was monitored with XO Score on a standard standard PTA balloon inflated to nominal pressure (12 ATM). Flow was restored and no residual stenosis or elastic recoil was present.
Angioplasty is traditionally used to dilate stenosed or narrowed dialysis fistulas and grafts to prolong use. Fistulas and grafts with difficult calcifying lesions can be particularly difficult to treat and are prone to complications, such as recoil and dissection. Treatment failure and complications can lead to early failure of fistulas and grafts.
ATP’s traditional cut, notch, and stress structure (CS) technologies are made with metal or polymer wires, spacers, blades, or grooves wrapped around or fused to the outside of the balloon of angioplasty. These wires, struts, blades, and/or grooves expand with the balloon to provide focal force into calcified, hyperplastic, and/or resistant lesions to prevent dissection, dilate resistant lesions, and/or prepare the vessel for another action. Traditional systems are bulky, difficult to use, prohibitively expensive and require a large inventory.
The XO Score is a thin, one-piece metal alloy exoskeleton sheath with up to 22 struts/grooves that slides over ready-to-use angioplasty balloons. When the angioplasty balloon is inflated, the struts/grooves expand with the balloon and rotate 90° to apply focal force to the vessel. When the balloon is deflated, the XO struts/grooves rotate 90° to an atraumatic position and the XO structure assists in repacking the balloon for removal.
XO’s technology can also be optimized to constrain balloons and prevent torsional and longitudinal shear during angioplasty balloon inflation.
dr. Richard Saxon from Tri-City Medical Center to San Diego, California shared, “I recently noticed some impressive results
using XO Score in critical recurrent brachiocephalic outflow stenosis and moderate central arch stenosis. The XO Score crossed both lesions without difficulty and allowed the use of a 5mm and 6mm PTA for effective lesion dilation with no evidence of post-treatment recoil. Dr. Saxon added, “XO Score introduces a new treatment option to help restore and maintain patency of arteriovenous fistulas and grafts in hemodialysis patients. »
The XO Score System is FDA cleared and CE marked for dilating stenotic material in the iliac, femoral, ilio-femoral, popliteal, infra-popliteal, and renal arteries and for the treatment of arterio-dialysis fistula obstructive lesions. native or synthetic vein.
Transit Scientific is a private company that designs, develops, and markets medical devices, including the FDA-approved XO score and CE mark.® and XO Cross® more XO Cath Interventional Oncology and XO CS Coronary System platforms in development. Transit Scientific has over 20 US and worldwide patents issued and pending. www.XOScore.com
Transit Scientific Media Contact: Kelly Himle (414) 736-1654, [email protected].
SOURCE Scientific Transit