Physical activity measured by device and possible association with heart failure


According to the results of a study published in Traffic.

The researchers sought to assess the dose-response relationship between the physical activity measured by the device and the HF stratified by the intensity of the physical activity.

They conducted a prospective cohort study that included 94,739 UK Biobank participants between 2013 and 2015 with device-measured physical activity and who initially had no history of HF and myocardial infarction. . Time spent in light, moderate, and vigorous-intensity physical activity was measured using a wrist-worn accelerometer. Hospital and death records were reviewed for the onset of HF. The researchers assessed adjusted sociodemographic and lifestyle associations using Cox proportional hazard models and concurrent risk with cause-specific hazard ratios (HRs).

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The researchers found that the overall incidence of heart failure (median follow-up, 6.1 years) was 98.5 per 10,000 person-years. There was a lower risk of CI in participants with 150-300 minutes/week of moderate-intensity physical activity (HR, 0.37; 95% CI, 0.34-0.41) and 75-150 min/week of vigorous-intensity physical activity (HR, 0.34; 95% CI, 0.25-0.46) compared with participants without moderate- or vigorous-intensity physical activity. They noted an inverted J-shaped association between vigorous-intensity physical activity and heart failure with a possible lower risk reduction above 150 min/week.

The limitations of the study include the fact that the UK biobank is not representative of the UK population and includes a possible selection bias for healthy volunteers. There is residual confounding, reverse causation, the lack of differentiation in wrist accelerometers between light physical activity and sedentary behavior. The study also lacks the ability to distinguish between HF with preserved ejection fraction and HF without.

“AP measured by the device [physical activity]in particular MPA [moderate-intensity physical activity], was associated with a lower risk of HF,” the study authors wrote. “VPA Associations [vigorous-intensity physical activity] should be carefully considered before considering the promotion of very high levels of VPA in the general population.

Disclosure: Some study authors have disclosed affiliations with biotechnology, pharmaceutical and/or device companies. Please see the original citation for a full list of author disclosures.


Ho FK, Zhou Z, Petermann-Rocha F, et al. Association between device-measured physical activity and incident heart failure: a prospective cohort study of 94,739 UK Biobank participants. Traffic. Published online August 29, 2022. doi:10.1161/CIRCULATIONAHA.122.059663


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